They also play a role in the immune system's inflammatory response and help the body respond to stress. These hormones, including cortisol, affect the body's ability to turn food into energy. The outer layer, called the cortex, makes a group of hormones called corticosteroids. The interior, called the medulla, makes adrenaline-like hormones. The adrenal glands are made up of two sections. Damage to these glands results in too little of the hormone cortisol and, often, the hormone aldosterone. As part of the endocrine system, they make hormones that affect almost every organ and tissue in the body. The adrenal glands sit just above the kidneys. Weight loss that doesn't happen on purposeĪddison's disease is caused by damage to the adrenal glands.Extreme loss of body water, also known as dehydration.See a health care provider if you have common symptoms of Addison's disease, such as: Severe abdominal pain, vomiting and diarrhea, leading to dehydration.Seek emergency treatment for the following: Acute adrenal failure can lead to life-threatening shock. Sometimes the symptoms of Addison's disease appear suddenly. Body hair loss or sexual issues in some peopleĪcute adrenal failure, known as addisonian crisis.Low blood sugar, also called hypoglycemia.Then a stress, such as illness or injury, makes symptoms worse. The disease can move so slowly that people who have it may ignore the symptoms at first.

Addison's disease symptoms usually happen slowly, often over months.

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